Table 1. The developed device can apply 25 separate mechanical stimulation conditions to cells.
| Condition number | Strain condition number | Trench shape | Trench dimensions | Orientation angle of trench major axis with respect to flow |
|---|---|---|---|---|
| 1 | 1 | circular | radius 1.25 mm | – |
| 2 | 2 | circular | radius 1.5 mm | – |
| 3 | 3 | circular | radius 1.75 mm | – |
| 4 | 4 | circular | radius 2 mm | – |
| 5 | 5 | circular | radius 2.5 mm | – |
| 6 | 6 | ellipse | half minor axis 1.55 mm half major axis 2.3 mm | 0° |
| 7 | 30° | |||
| 8 | 45° | |||
| 9 | 60° | |||
| 10 | 90° | |||
| 11 | 7 | ellipse | half minor axis 1.7 mm half major axis 2.3 mm | 0° |
| 12 | 30° | |||
| 13 | 45° | |||
| 14 | 60° | |||
| 15 | 90° | |||
| 16 | 8 | ellipse | half minor axis 1.9 mm half major axis 2.3 mm | 0° |
| 17 | 30° | |||
| 18 | 45° | |||
| 19 | 60° | |||
| 20 | 90° | |||
| 21 | 9 | ellipse | half minor axis 2.1 mm half major axis 2.3 mm | 0° |
| 22 | 30° | |||
| 23 | 45° | |||
| 24 | 60° | |||
| 25 | 90° |
The conditions are listed here and assigned a condition number each for ease of identification. In the absence of flow, the variously oriented strain conditions are identical and hence a strain condition number is also defined to collectively refer to these identical strain conditions.