Table 2.
Comparison of underlying conditions reported among influenza A (H1N1)pdm09‐associated deaths by age group, United States, September–October, 2009, n = 302
| Co‐morbid conditions | All ages Frequency (%) | <18 years Frequency (%) | ≥18 years Frequency (%) |
|---|---|---|---|
| Medical history reported | 297/302 (98) | 43/45 (96) | 254/257 (99) |
| Chronic lung disease | 110/297 (37) | 16/43 (37) | 94/254 (37) |
| Asthma | 52/297 (18) | 11/43 (26) | 41/254 (16) |
| COPD | 49/297 (17) | 0/43 (0) | 49/254 (19) |
| Other chronic lung | 44/297 (15) | 11/43 (26) | 33/254 (13) |
| Cardiovascular disease | 70/297 (24) | 9/43 (21) | 61/254 (24) |
| Neurologic disorder | 62/297 (21) | 15/43 (35) | 47/254 (19) |
| Developmental delay | 23/297 (7·7) | 13/43 (30) | 10/254 (3·9) |
| Neuromuscular disorder | 29/297 (9·8) | 8/43 (19) | 21/254 (8·3) |
| Seizure disorder | 27/297 (9·1) | 11/43 (26) | 16/254 (6·3) |
| Other neurologic | 30/297 (10) | 3/43 (7·0) | 27/254 (11) |
| History of stroke | 10/297 (3·4) | 0/43 (0) | 10/254 (3·9) |
| Pregnant | 1/297 (0·34) | 0/43 (0) | 1/254 (0·39) |
| 6 weeks post‐partum | 7/297 (2·4) | 0/43 (0) | 7/254 (2·8) |
| Metabolic disorders | 87/297 (29) | 3/43 (7) | 84/254 (33) |
| Diabetes | 75/297 (25) | 0/43 (0) | 75/254 (30) |
| Other metabolic | 19/297 (6·4) | 3/43 (7) | 16/254 (6·3) |
| Immunosuppressive condition* | 58/297 (20) | 1/43 (2·3) | 57/254 (22) |
| HIV/AIDS | 6/297 (2·0) | 0/43 (0) | 6/254 (2·4) |
| Renal disease | 41/297 (14) | 2/43 (4·7) | 39/254 (15) |
| Hematologic disorder | 33/297 (11) | 0/43 (0) | 33/254 (13) |
| Hepatic disease | 19/297 (6·4) | 0/43 (0) | 19/254 (7·5) |
| ACIP condition** | 214/297 (72) | 27/43 (63) | 187/254 (74) |
| Obesity*** | 139/251 (55) | 8/30 (27) | 131/221 (59) |
| Morbid obesity† | 56/221 (25) | – | 56/221 (25) |
| ACIP condition or obesity | 247/297 (83) | 30/43 (70) | 217/254 (85) |
| History of alcohol/substance abuse | 33/184 (18) | 0/37 (0) | 33/147 (22) |
| Current smoker | 38/213 (18) | 0/38 (0) | 38/175 (22) |
ACIP, Advisory Committee on Immunization Practices.
*Includes chemotherapy and other medications, but does not include persons with HIV infection or AIDS.
**Conditions include chronic pulmonary (including asthma), cardiovascular (excluding hypertension), renal, hepatic, neurologic/neuromuscular, pregnancy or child delivery within 6 weeks, hematologic, and metabolic (including diabetes mellitus) disorders, immune suppression (including immune suppression caused by medications or human immunodeficiency virus).
***Not defined in patients aged <2 years; includes H1N1pdm09‐associated deaths also defined as morbidly obese.
†Not defined in patients aged <18 years.