Table 3.
Pathways enriched in low and high milk-yield groups.
| KEGG pathways | Group | Genes | FDR p-value |
|---|---|---|---|
| Oxidative phosphorylation | L | 33 | 1.53E-07 |
| Toll-like receptor signalling pathway* | L | 20 | 3.39E-05 |
| H | 13 | 4.54E-03 | |
| Cytokine-cytokine receptor interaction | L | 26 | 1.08E-04 |
| Jak-STAT signalling pathway | H | 18 | 1.96E-04 |
| Melanogenesis | L | 14 | 6.75E-04 |
| Spliceosome | L | 21 | 9.81E-04 |
| Viral myocarditis | L | 11 | 1.03E-03 |
| Wnt signaling pathway | H | 17 | 1.91E-03 |
| RIG-I-like receptor signaling pathway | L | 12 | 2.99E-03 |
| Osteoclast differentiation | L | 17 | 3.25E-03 |
| Toxoplasmosis | L | 17 | 3.25E-03 |
| Adipocytokine signaling pathway | L | 12 | 3.40E-03 |
| Protein digestion and absorption | L | 10 | 3.91E-03 |
| ErbB signaling pathway | H | 10 | 4.14E-03 |
| Natural killer cell mediated cytotoxicity | H | 13 | 4.36E-03 |
| Leukocyte transendothelial migration | H | 14 | 4.43E-03 |
| Cell cycle | L | 17 | 4.87E-03 |
| MAPK signaling pathway* | L | 27 | 5.01E-03 |
| H | 21 | 5.28E-03 | |
| Vasopressin-regulated water reabsorption | L | 9 | 6.02E-03 |
| VEGF signaling pathway | H | 10 | 6.79E-03 |
| Collecting duct acid secretion | L | 7 | 7.38E-03 |
| Axon guidance | L | 15 | 7.50E-03 |
| Apoptosis | L | 13 | 7.56E-03 |
| Cell adhesion molecules (CAMs) | L | 15 | 8.50E-03 |
| Protein processing in endoplasmic reticulum | L | 20 | 9.14E-03 |
Notes:
L, Low milk-yield; H, High milk-yield.
*
Common pathways in L and H groups.