Table 2. Activities of glycolytic enzymes.
Rats received an i.p. injection of FDP (2 mg/kg) 30 min prior to reperfusion. Enzyme activities are expressed in milliunits/µg protein and data are presented as mean ± SD (n = 6). Data analysis was determined by the one way analysis of variance (ANOVA) accompanied by the Holms-Sidak multiple comparisons test.
| Sham | tIRI | p valuea | FDP | p valueb | ||
|---|---|---|---|---|---|---|
| HK1 | I | 2.08 ± 0.30 | 1.11 ± 0.27 | 0.0034 | 1.87 ± 0.38 | 0.0260 |
| C | 1.72 ± 0.43 | 1.71 ± 0.48 | ns | 1.55 ± 0.70 | ns | |
| GPI | I | 0.91 ± 0.11 | 0.77 ± 0.12 | 0.2046 | 0.71 ± 0.16 | 0.8686 |
| C | 0.73 ± 0.14 | 0.88 ± 0.10 | ns | 0.79 ± 0.09 | ns | |
| PFK1 | I | 1.33 ± 0.24 | 0.78 ± 0.10 | 0.016 | 1.30 ± 0.17 | 0.0029 |
| C | 1.2 ± 0.21 | 1.08 ± 0.30 | ns | 1.42 ± 0.25 | ns | |
| GAPDHS | I | 1.49 ± 0.14 | 1.05 ± 0.21 | 0.0016 | 1.46 ± 0.28 | 0.0040 |
| C | 1.36 ± 0.15 | 1.32 ± 0.18 | ns | 1.37 ± 0.16 | ns | |
| PGK2 | I | 0.98 ± 0.21 | 0.77 ± 0.09 | 0.1388 | 0.81 ± 0.14 | 0.9894 |
| C | 0.92 ± 0.19 | 0.84 ± 0.15 | ns | 0.83 ± 0.17 | ns | |
| LDHC | I | 2.02 ± 0.41 | 1.07 ± 0.17 | <0.0001 | 1.78 ± 0.19 | 0.0017 |
| C | 2.02 ± 0.34 | 2.02 ± 0.16 | ns | 1.84 ± 0.43 | ns |
Notes.
tIRI compared to sham.
FDP compared to tIRI.
- I
- Ipsilateral
- C
- Contralateral