Skip to main content
. 2016 Apr 18;25(6):1138–1146. doi: 10.1002/pro.2931

Figure 4.

Figure 4

Biological examples of order‐disorder transitions between protein conformations. The region suffering order‐disorder transition is coloured in red. (a) Protein DivK conformations present an order‐disorder transition between apo (PDB code: 1M5T_A ‐ color blue) and holo (PDB code: 1MB0_A ‐ color cyan) forms. These structures present a C‐apha RMSD of 0.345 A. (b) Enzyme dihydropteroate synthase (DHPS) shows an order‐desorden transition in the conformers PDB code: 3TYZ_B (color blue) and 3TZN (color cyan). These structures present a C‐alpha RMSD of 0.548 A. (c) Conformers of human Transthyretin (TTR), (c1) Apo form (PDB code: 1TTA_B ‐ color blue) and holo form (PDB code: 3D2T_B ‐ color cyan) in complex with diflunisal. (c2) Apo conformation of TTR (PDB code: 1TTA_B ‐ color blue) and apo form (PDB code: 3CBR_B ‐ color cyan) at pH 3.5.