Table 1.
Human TFs predicted for the two conserved promoter motifs in the violet module.
| Motif | TF name | Class | Family | Score | Percent score |
|---|---|---|---|---|---|
| 49-base motif | ZNF263 | Zinc-coordinating | ββα-zinc finger | 36.811 | 87.646 |
| RREB1 | Zinc-coordinating | ββα-zinc finger | 33.664 | 84.161 | |
| ESR1 | Zinc-coordinating | Hormone-nuclear receptor | 33.618 | 84.045 | |
| REST | Zinc-coordinating | ββα-zinc finger | 32.833 | 78.173 | |
| PAX5 | Helix-turn-helix | Homeo | 32.654 | 85.931 | |
| 14-base motif | SP2 | Zinc-coordinating | ββα-zinc finger | 24.495 | 87.483 |
| ESR1 | Zinc-coordinating | ββα-zinc finger | 23.501 | 83.933 | |
| TP63 | Zinc-coordinating | Loop-sheet-helix | 23.084 | 82.443 | |
| ZNF263 | Zinc-coordinating | ββα-zinc finger | 23.082 | 82.435 | |
| EGR1 | Zinc-coordinating | ββα-zinc finger | 22.879 | 81.711 |
Top five predicted human TFs of the 49-base motif and 14-base motif from complete graph of violet module of AD APOE ε4 carriers.