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. Author manuscript; available in PMC: 2017 Jan 1.
Published in final edited form as: Expert Opin Ther Pat. 2016;26(3):323–345. doi: 10.1517/13543776.2016.1154045

Figure 6.

Figure 6

Chemical structures of phenylalanine-based FXIa inhibitors claimed by Merck with spiro-structures. Numbers in brackets represent the Ki values toward FXIa.