Table 1.
Baseline characteristics of trials and patient
| Characteristic | Blue | Orange | Patient | |
|---|---|---|---|---|
| Age mean±SD | 64.05±11 | 62.75±14.4 | 40 | |
| Men% | 78.7 | 53.9 | female | |
| Ethnic origin% | European | 90.55 | 100 | black |
| Black | 5 | 0 | ||
| Other | 4.45 | 0 | ||
| NYHA class (%) | ii | 24.1 | 33.5 | class ii |
| iii | 72.85 | 66.5 | ||
| iv | 3.05 | 0 | ||
| LV ejection fraction (%) mean±SD | 28±7.5 | 29.8±7.65 | 40 | |
| Heart rate (beats/min) mean±SD | 73.55±13.1 | 67.8±8.6 | 98 | |
| Blood pressure (mm Hg) mean±SD | Systolic | 125.15±18.6 | 125.4±8.1 | 96 |
| Diastolic | 75.1±10.75 | 81±6.45 | 58 | |
| Body-mass index (kg/m2) mean±SD | 27.85±5.3 | n/a | 21 | |
| Time on HD monthes mean±SD | n/a | 93.95±16.1 | None | |
| Body surface area mean±SD | n/a | 1.88±0.115 | 1.7 | |
| Delta body weight, kg mean±SD | n/a | 2.75±0.8 | n/a | |
| Heart-failure cause % | Ischaemic | 62.4 | n/a | idiopathic |
| Idiopathic | 26.2 | n/a | ||
| Hypertensive | 6.5 | n/a | ||
| Hospital admission for CHF | 77.1 | n/a | yes | |
| Myocardial infarction | 55.65 | 56.9 | no | |
| Current angina pectoris | 20.25 | n/a | no | |
| Stroke | 8.65 | n/a | no | |
| Diabetes mellitus | 29.75 | 29 | no | |
| Hypertension | 48.2 | n/a | no | |
| Atrial fibrillation | 26.95 | n/a | yes | |
| Pacemaker | 9.1 | n/a | no | |
| Current smoker | 16.85 | 12 | no | |
| previous smoker | n/a | 26.95 | no | |
| PCI | 14.75 | n/a | no | |
| CABG | 24.45 | n/a | no | |
| Implantable cardioverter-defibrillator | 3.95 | n/a | no | |
| Cancer | 6 | n/a | no | |
| Medical treatment % | ||||
| ACE inhibitor | 99.9 | 100 | yes | |
| Diuretic | 90.05 | n/a | yes | |
| ⍰ blocker | 55.45 | 60.95 | no | |
| Spironolactone | 17.15 | n/a | yes | |
| Digoxin/digitalis glycoside | 58.4 | 51.5 | no | |
| Calcium antagonist | 10.45 | n/a | no | |
| Other vasodilators | 36.75 | n/a | no | |
| Nitrates | n/a | 48 | no | |
| Oral anticoagulant | 38.1 | n/a | no | |
| Antiarrhythmic agent | 12.55 | n/a | no | |
| Amiodarone | n/a | 19.15 | no | |
| Aspirin | 51.45 | 63.85 | yes | |
| Other antiplatelet agent | 3.25 | 32.75 | no | |
| Lipid-lowering drug | 41.2 | n/a | statin | |
| Statin | n/a | 67.95 | statin | |
| Hemoglobin, g/dl mean±SD | n/a | 11.4±0.65 | 10 | |
| Albumin, g/dl mean±SD | n/a | 3.915±0.58 | 3.1 | |
| PTH, ng/l mean±SD | n/a | 245.9±36 | 220 | |
Exclusion: not specified