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. 2016 Jul 12;12(7):e1005013. doi: 10.1371/journal.pcbi.1005013

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© 2016 Chasman et al

This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

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Fig 4 — A. Modules conserved between human and mouse. There were fifteen (red shading) significantly overlapping module pairs (hypergeometric p-value < 0.0001), including 12 human modules and 13 mouse modules. B. A core set of interactions conserved between the human and mouse consensus regulatory networks. Shown are the 48 of 96 shared interactions that belong to subnetworks with at least three nodes. Shading indicates Calu-3 ISGs (violet) and nodes identified both as known host genes and ISGs (magenta). Star indicates a gene that significantly impacted viral replication on knockdown as identified in this study.