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. 2016 Jul 12;11(7):e0158946. doi: 10.1371/journal.pone.0158946

Table 4. Receiver operating characteristic curve (ROC) analysis for the set of 5 microRNAs for differentiating TNBC in tissues and sera.

(a) ROC for TNBC tissues (n = 23)
miRNA Sensitivity Specificity AUC (95% CI) P value
miR-21 100% 95% 0.9977 (0.9903–1.000) p < 0.0001*
miR-221 100% 100% 1.000 (1.000–1.000) p < 0.0001*
miR-210 95% 95% 0.9783 (0.9347–1.022) p < 0.0001*
miR-195 73% 78% 0.7580 (0.6058–0.9103) p = 0.0027*
miR-145 73% 60% 0.7013 (0.5489–0.8538) p = 0.0193*
Let-7a 95% 95% 0.9773 (0.9411–1.014) p < 0.0001*
(b) ROC for TNBC sera (n = 23)
miR-21 95% 81% 0.9587 (0.9071–1.000) p < 0.0001*
miR-221 81% 72% 0.8099 (0.6629–0.9570) p = 0.0004*
miR-210 100% 100% 0.9979 (0.9911–1.000) p < 0.0001*
miR-195 78% 65% 0.6767 (0.5098–0.8437) p = 0.0400*
miR-145 78% 91% 0.8837 (0.7862–0.9812) p < 0.0001*
Let-7a 91% 86% 0.9660 (0.9237–1.008) p < 0.0001*

AUC: Area Under the Curve; CI: Confidence Interval;

* Significant.