Table 2.
Fitting parameters for the gap-derived strand memory experiment with MutSα mutants
%gap [95% Confidence Interval] | %A→G repair [95% Confidence Interval] | |||||
---|---|---|---|---|---|---|
t1/2 (min) | %gap at 0 min | R2 | t1/2 (min) | %repair at 0 min | R2 | |
+buffer | 1.44 [0.51−0.73] | 100 [95.2−104.7] | 0.99 | 2.94 [2.32−3.98] | 75.7 [69.2−82.2] | 0.97 |
+xMutSαWT | 1.35 [0.58−0.81] | 100 [95.1−104.9] | 0.99 | 25.5 [17.6−46.1] | 84.8 [80.5−89.2] | 0.98 |
+xMutSαPIP | 1.48 [1.18−2.00] | 100 [95.4−104.6] | 0.99 | 12.5 [10.9−14.7] | 81.9 [78.5−85.4] | 0.99 |
+xMutSαΔN | 1.43 [1.14−1.93] | 100 [95.6−104.4] | 0.99 | 12.3 [11.3−13.6] | 81.9 [79.8−84.0] | 1.00 |
Parameters for the one-phase exponential decay fitting of the data described in Figure 9B and D are presented. %gap: percentage of remaining gaps (100 - %closed), t1/2: half-life, R2: coefficient of determination. n = 3.