Table 1.
Distribution of Selected Factors in Controls and in Prostate Cancer Patients Stratified by TMPRSS2:ERG Fusion Status
| TMPRSS2:ERG Fusion Status | ||||
|---|---|---|---|---|
| Controls | Negative | Positive | P-value* | |
| N (%) | N (%) | N (%) | ||
| Total | 942(100) | 175 (100) | 171 (100) | |
| Age | ||||
| 35 -- 49 | 93 (10) | 20 (11) | 38 (22) | < 0.01 |
| 50 -- 54 | 113 (12) | 25 (14) | 25 (15) | |
| 55 -- 59 | 174 (18) | 33 (19) | 36 (21) | |
| 60 -- 64 | 187 (20) | 42 (24) | 43 (25) | |
| 65 -- 69 | 202 (21) | 33 (19) | 22 (13) | |
| ≥ 70 | 170 (18) | 22 (13) | 7 (4) | |
| Race | ||||
| Caucasian | 844 (90) | 150 (86) | 157 (92) | 0.07 |
| African American | 98 (10) | 25 (14) | 14 (8) | |
| Family History of Prostate Cancer | ||||
| No | 833 (88) | 128 (73) | 130 (76) | 0.54 |
| Yes | 109 (12) | 47 (27) | 41 (24) | |
| Body Mass Index | ||||
| < 25.0 | 259 (27) | 53 (30) | 55 (32) | 0.87 |
| 25.0 -- 29.0 | 444 (47) | 92 (53) | 85 (50) | |
| ≥ 30.0 | 239 (25) | 30 (17) | 31 (18) | |
| Smoking Status | ||||
| Non-smoker | 429 (46) | 78 (45) | 81 (47) | 0.8 |
| Former smoker | 394 (42) | 86 (49) | 78 (46) | |
| Current smoker | 118 (13) | 11 (6) | 12 (7) | |
| PSA tests in the 5 years preceding reference date | ||||
| None | 231 (30) | 31 (19) | 44 (27) | 0.14 |
| 1 -- 2 | 168 (22) | 30 (18) | 26 (16) | |
| 3 -- 4 | 129 (17) | 32 (20) | 40 (24) | |
| ≥ 5 | 251 (32) | 70 (43) | 54 (33) | |
| Diagnostic PSA** | ||||
| < 4.0 | 21 (13) | 38 (23) | 0.03 | |
| 4.0 -- 9.9 | 110 (65) | 99 (60) | ||
| ≥ 10.0 | 37 (22) | 27 (16) | ||
| Gleason Sum | ||||
| ≤ 6 | 73 (42) | 79 (46) | 0.03 | |
| 7 (3 + 4) | 62 (35) | 71 (42) | ||
| 7 (4 + 3) | 25 (14) | 9 (5) | ||
| 8 -- 10 | 15 (9) | 12 (7) | ||