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ApoE Levels in the Brain in Target Replacement Mice by ApoE Genotype
| Genotype | Frontal Cortex, ng/mg44 | Hippocampus, ng/mg44 |
|---|---|---|
| Human apoE2/2 | ≈120* | ≈180† |
| Human apoE3/3 | ≈90 | ≈160 |
| Human apoE4/4 | ≈75 | ≈150 |
33% higher than apoE3 and 40% higher than apoE4.
12.5% higher than apoE3 and 20% higher than apoE4.
