Hematological analysis of mice treated with GPMs. Blood enzyme levels of female nude athymic mice were acquired 1 day, 7 days, 1 month, and 3 months days post-injection of 150 mg Au/kg of 0.9 nm GPMs (grey) or 5 nm GPM (black). Grey dotted lines denote the “normal” analyte levels. The specific enzymes analyzed were (A) alkaline phosphatase (ALKP), (B) alanine transaminase (ALT), (C) aspartate aminotransferase (AST), and (D) total bilirubin (TBIL).