Table 2.
Arrival Measures and Infusion BrAC levels
| Ivermectin | Placebo | |
|---|---|---|
| Arrival Measures | ||
| BAI | 1.64 (2.73) | 0.45 (0.82) |
| BDI | 3.00 (4.22) | 3.00 (4.15) |
| PACS | 13.82 (6.54) | 12.45 (6.64) |
| POMS | ||
| Tension | 0.73 (0.43) | 0.79 (0.79) |
| Vigor | 1.64 (0.69) | 1.36 (0.91) |
| Negative Affect | 0.55 (0.42) | 0.57 (0.32) |
| Positive Affect | 2.54 (1.28) | 2.04 (0.92) |
| Target BrAC (g/dl) | ||
| Infusion | ||
| 0.02 | 0.022 (0.002) | 0.022 (0.003) |
| 0.04 | 0.041 (0.002) | 0.041 (0.013) |
| 0.06 | 0.063 (0.002) | 0.062 (0.002) |
| 0.08 | 0.083 (0.002) | 0.081 (0.001) |
| Post-infusion | ||
| 0.06 | 0.057 (0.003) | 0.059 (0.003) |
| 0.04 | 0.040 (0.002) | 0.040 (0.003) |
| Time to reach target BrAC from previous timepoint (minutes) | ||
| Infusion | ||
| 0.02 | 13 (2) | 12 (2) |
| 0.04 | 18 (4) | 18 (4) |
| 0.06 | 26 (4) | 25 (5) |
| 0.08 | 29 (9) | 28 (5) |
| Post-infusion | ||
| 0.06 | 21 (9) | 22 (6) |
| 0.04 | 55 (21) | 58 (27) |
Data are mean (SD)
BAI – Beck Anxiety Inventory; BDI – Beck Depression Inventory; PACS – Penn Alcohol Craving Scale; POMS – Profile of Mood States, 40 item version POMS was assessed at 9:00 AM, all other Arrival Measures were collected at 8:00 AM.