Table 2.
Compound | hCAII | hCAI | hCAIXa |
---|---|---|---|
IC50 (nM) | IC50 (nM) | IC50 (nM) | |
1 | 1951 ± 4 | 3526 ± 6 | 3240 ± 4 |
2 | 112 ± 3 | 810 ± 3 | 1052 ± 4 |
7 | 104 ± 3 | 430 ± 3 | 963 ± 4 |
9 | 764 ± 2 | 120 ± 3 | 981 ± 3 |
12 | 210 ± 3 | 755 ± 2 | 880 ± 5 |
see SI, Fig. S9
Compound | hCAII | hCAI | hCAIXa |
---|---|---|---|
IC50 (nM) | IC50 (nM) | IC50 (nM) | |
1 | 1951 ± 4 | 3526 ± 6 | 3240 ± 4 |
2 | 112 ± 3 | 810 ± 3 | 1052 ± 4 |
7 | 104 ± 3 | 430 ± 3 | 963 ± 4 |
9 | 764 ± 2 | 120 ± 3 | 981 ± 3 |
12 | 210 ± 3 | 755 ± 2 | 880 ± 5 |
see SI, Fig. S9