Table I.

Demographic clinical and outcome characteristics of the women who provided AF samples for NGAL, MMP-9 and NGAL•MMP-9 complex (n=308).

Variable	2nd trimester genetic amniocenteses n = 23	3rd trimester lung maturity amniocenteses n = 25	Rule-out infection amniocenteses n = 260	P value
Characteristics at amniocentesis
Maternal age, years, †	34 [30 – 39]	30 [26 – 34]	27 [22 – 33]	<0.001
Parity †	0 [0 – 1]	1 [0 – 2]	1 [0 – 1]	0.018
Gravidity †	2 [1 – 3]	3 [2 – 4]	2 [1 – 4]	0.384
GA, weeks †	19 [17 – 20]	36 [35 – 37]	29 [25 – 31]	<0.001
Uterine contractions ‡	0 (0)	0 (0)	127 (50)	<0.001
Cervical dilatation > 3 cm ‡	0 (0)	0 (0)	46 (18)	0.007
PPROM ‡	0 (0)	0 (0)	121 (47)	<0.001
Clinical chorioamnionitis ‡	0 (0)	0 (0)	19 (7)	0.153
Outcome characteristics
Term delivery (≥ 37 weeks) ‡	23 (100)	13 (52)	43 (17)	<0.001
Preterm birth at < 34 weeks ‡	0 (0)	0 (0)	204 (78)	<0.001
GA at delivery, weeks †	39 [39 – 41]	37 [36 – 37]	31 [26 – 33]	<0.001
Amniocentesis-delivery time, days †	144 [137 – 156]	2 [1 – 8]	2 [0 – 16]	<0.001

^†Data presented as median [interquartile range] and analyzed by Kruskal-Wallis ANOVA on Ranks.

^‡Data presented as n (%) and analyzed by Chi square tests.

Abbreviations: PPROM, preterm premature rupture of membrane; GA, gestational age