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. Author manuscript; available in PMC: 2017 Apr 1.
Published in final edited form as: Front Neuroendocrinol. 2016 Mar 9;41:99–113. doi: 10.1016/j.yfrne.2016.02.004

Figure 2.

Figure 2

Sagittal section of the rodent brain showing the two main regions where neurogenesis occurs in the adult brain, the dentate gyrus (DG) of the hippocampus and the olfactory bulb (OB). In the OB (Figure 2a), neural stem cells residing in the SVZ proliferate (1) then migrate a great distance along the RMS (2) to reach the OB where they become mostly local inhibitory interneurons (3). In the DG (Figure 2b), progenitor cells proliferate in the SGZ (1) then migrate a short distance into the GCL (2) where a percentage will survive and mature, becoming glutamatergic granule neurons that extend axons to the CA3 region of the hippocampus (3). Adapted from Borsini et al., 2015.