Fig. 2.

Gibbs free energy and the probability of 5-year survival. Data from the TCGA gene list were overlaid on BioGRID® in order to merge protein–protein interaction network data with transcription data using Eq. (3). As evident, Gibbs free energy can be correlated with 5-year survival with an r coefficient of –0.72. We have excluded KIRC and KIRP because the biology of neuroectodermal and epithelial cancers differ from KIRC and KIRP. The inclusion of KIRC and KRIP in the calculation decreased correlation to –0.21