FIGURE 3.

Host immune cell response in corticosteroid treated (CT) mice after A. fumigatus infection. Flow cytometric analysis of lungs from immunocompetent (IC) and CT mice non-infected (NI) or infected (I) with 1 × 10⁶ A. fumigatus conidia were euthanized at indicated time points. (A) In vivo neutrophil, (B) macrophage, (C) dendritic cell, and (D) monocyte recruitment to the lung at 4 h p.i. (E–H) In vivo recruitment of immune cells to the lung at 4, 16, and 40 h. p.i.: (E) neutrophils, (F) macrophages, (G) dendritic cells, and (H) monocytes. Data are pooled from three independent experiments with at least n = 3/group of mice in each experiment. Unpaired Mann–Whitney u-test was utilized to determine significant differences: ^∗P < 0.05; ^∗∗P < 0.01; ^∗∗∗P < 0.001.