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. 2016 Jul 11;6:29703. doi: 10.1038/srep29703

Figure 2. Gene expression of BMP type II receptors in response to BMP-7.

Figure 2

Box plots represent qRT-PCR results given as mean normalised expression relative to 18S rRNA and the untreated control (reference line) using an efficiency corrected formula. Symbols indicate significant differences to the untreated control (n = 6). (A) BMPR-II expression was strongly increased after 2 to 8 h of BMP-7 stimulation which was more pronounced in the high BMP-7 group (*p = 0.002. (B) The expression of ActR-IIa was increased in the low BMP-7 group after 1 h, in the high BMP-7 group after 2 h and 4 h after stimulation by both concentrations (#p = 0.03, *p = 0.004). (C) ActR-IIb expression was significantly down regulated after 2 h and 4 h compared to the untreated control (*p = 0.002).