Skip to main content
. 2016 Jul 11;7:12134. doi: 10.1038/ncomms12134

Table 1. Adoptive transfer of CpG-proB cells but not of control pro-B cells inhibits ongoing EAE.

Group Mice Mean maximum score±s.e.m. Day of onset±s.e.m. Disease incidence
Control 30 3.51±0.89 13.56±1.40 100%
WT CpG-proBs 30 1.56±1.26** 14.50±2.22 76.7%*
Control ProBs 20 3.57±0.92 13.30±2.22 100%
PBS-proBs 4 3.50±0.05 12.00±0.00 100%

Clinical parameters from data in Fig. 1e, including the maximum clinical score (mean±s.e.m.) of each treatment group and the day of disease onset (mean±s.e.m.) among mice with EAE as well as the disease incidence over the entire observation period (35 days). Control mice received PBS injection instead of progenitor injection. Significant differences between CpG-proB recipients versus control mice are indicated; *P<0.05, **P<0.005, assessed by non-parametric Mann–Whitney's t-test.