Table 4.

Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway enrichment analysis of genes in key modules based on false discovery rate (FDR) < 0.01 and gene count ≥ 10.

Modules	KEGG pathways	Gene count	FDR
Module 1	Neuroactive ligand-receptor interaction	15	8.32E − 06
Module 2	Neuroactive ligand-receptor interaction	37	7.10E − 26
Module 3	Neuroactive ligand-receptor interaction	10	1.63E − 03
Module 4	Cytokine-cytokine receptor interaction	29	6.91E − 16
	JAK-STAT signaling pathway	20	1.73E − 11
	Toll-like receptor signaling pathway	11	4.32E − 05
	Natural killer cell mediated cytotoxicity	12	6.04E − 05
Module 5	Neuroactive ligand-receptor interaction	10	3.76E − 03
Module 6	Neuroactive ligand-receptor interaction	33	4.62E − 25
Module 7	Neuroactive ligand-receptor interaction	16	2.11E − 07
Module 8	Steroid hormone biosynthesis	11	4.36E − 09