Table 1.

The original values of nine physicochemical properties used in this study.

Amino acids	Hydrophobicity	Hydrophilicity	Rigidity	Flexibility	Irreplaceability	Mass	pI	pK(α-COOH)	pK(α-NH3 +)
A	0.62	−0.5	−1.338	−3.102	0.52	15	6.11	2.35	9.87
C	0.29	−1	−1.511	0.957	1.12	47	5.02	1.71	10.78
D	−0.9	3	−0.204	0.424	0.77	59	2.98	1.88	9.6
E	−0.74	3	−0.365	2.009	0.76	73	3.08	2.19	9.67
F	1.19	−2.5	2.877	−0.466	0.86	91	5.91	2.58	9.24
G	0.48	0	−1.097	−2.746	0.56	1	6.06	2.34	9.6
H	−0.4	−0.5	2.269	−0.223	0.94	82	7.64	1.78	8.97
I	1.38	−1.8	−1.741	0.424	0.65	57	6.04	2.32	9.76
K	−1.5	3	−1.822	3.950	0.81	73	9.47	2.2	8.9
L	1.06	−1.8	−1.741	0.424	0.58	57	6.04	2.36	9.6
M	0.64	−1.3	−1.741	2.484	1.25	75	5.74	2.28	9.21
N	−0.78	0.2	−0.204	0.424	0.79	58	10.76	2.18	9.09
P	0.12	0	1.979	−2.404	0.61	42	6.3	1.99	10.6
Q	−0.85	0.2	−0.365	2.009	0.86	72	5.65	2.17	9.13
R	−2.53	3	1.169	3.060	0.60	101	10.76	2.18	9.09
S	−0.18	0.3	−1.511	0.957	0.64	31	5.68	2.21	9.15
T	−0.05	−0.4	−1.641	−1.339	0.56	45	5.6	2.15	9.12
V	1.08	−1.5	−1.641	−1.339	0.54	43	6.02	2.29	9.74
W	0.81	−3.4	5.913	−1.000	1.82	130	5.88	2.38	9.39
Y	0.26	−2.3	2.714	−0.672	0.98	107	5.63	2.2	9.11