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| Constructs | CNGA4 | CNGB1b | ||
|---|---|---|---|---|
| fcGMP | fcGMP | fcAMP | fHcAMP | |
| 10 μM | 10 μM | 10 μM | 2 μM | |
| CNGA4* | − | |||
| CNGB1b* | − | |||
| CNGA2RE:A4* | + | |||
| CNGA2TM:A4 | + | |||
| CNGA2TM:A4RE* | − | |||
| CNGA2RE:B1b | − | − | − | |
| CNGA2TM:B1b | − | |||
| CNGA2RE:A4RE:B1b | − | + | + | |
| CNGA2RE:A4RE:B1bRE | − | − | − | |
| CNGA2TM:A4RE:B1b | − | + | ||
| CNGA2TM:A4RE:B1bRE | − | − | ||
*from Nache et al., 2012.
The symbols “+” and “−” indicate that ligand binding to the respective modulatory subunits was either observed or not.
