Table 3.
Chimeric peptides from Table 1 with regular part matching proteins translated from known mitogenome-encoded genes. Swinger parts are underlined, gene identity is followed by the position of the ‘normal’ part of the peptide matching the regular translation of the gene in the regular protein. The swinger transformation and the amino acid inserted at stop(s) are also indicated. Peptide parts matching translation according to both nuclear and mitochondrial genetic codes are highlighted: peptide 100 could be translated in the cytosol on the base of RNA transcribed from mitochondrial inserts in the nuclear chromosome (numts), all remaining peptides could not, as at least on part of the peptide is incompatible with translation according to the nuclear genetic code. Analyses (see text) show that there are fewer detected peptides compatible with the nuclear genetic code than expected, and more than expected peptides compatible only with the mitochondrial genetic code.
Table 1 # | Peptide | Gene | Position | Swinger rule | Stop |
---|---|---|---|---|---|
100 | GASFLFIWNSLYLLFGAWAGVLGTALSLLIRAELGQPGNL | COX1 | 18–47 | A > T > G | r |
27 | SGWVEWSRHSVLLLLSLPVLAAGITMLLTDR | COX1 | 205–213 | A ↔ C + G ↔ T | s |
181 | LLKECLSLASVPATPPYHTFEEPVYMK | COX1 | 500–512 | A > T > G > C | x |
136 | NQMIQALLITILLGLYFTLLSIVTAGTVFGLR | COX3 | 157–168 | A > C > T > G | e |
169 | AASHPVPVPMTLLMLGLLTNTLTMYQWWR | COX3 | 41–59 | A > T > C > G | a |
23 | DVSGPSSPSSSLMTLTLFSPDLLGDPDNYTLANPLNTPPY | Cyt B | 238–267 | C ↔ T | y |
19 | NPSLSISVPSTRHVSMPITISSIPPQTTEMCLMK | ND1 | 305–318 | C ↔ T | t |
38 | WALFLSGTDSSSVSLAPLAATGSWGGLNQTQLR | ND2 | 165–176 | A ↔ G + C ↔ T | n |
34 | SLKQNWDFSFNSSTMVVAGIFLLIR | ND5 | 249–262 | A ↔ C + G ↔ T | f |
80 | IVAFSTSSQLGLMVLEVPVGVK | ND5 | 301–313 | A > G > T > C | d |
7 | LLGAVPLASASLTIGSLALAGMPFLTGFYSKDHIIETANMS | ND5 | 374–402 | A ↔ G |