Table 1.
Initial medical therapy (n = 115) |
|||||
Clinical details | Early surgery (n = 42) | IMT (n =115) | P value | DS (n = 62)1 | P value |
Gender M:F | 22:20 | 50:65 | 0.531 | 24:38:00 | 0.227 |
Age at diagnosis (yr), median (IQR) | 34.5 (24-46) | 24 (19-33) | 0.0001 | 23.5 (18.25-31.75) | 0.006 |
Smoking | 15 (35.7) | 43 (37.4) | 0.852 | 25 (40.3) | 0.685 |
Phenotype | |||||
B1 (non-stricturing) | 3 (7.1) | 38 (36.2) | 0.001 | 4 (6.5) | 0.968 |
B2 (stricturing) | 17 (40.5) | 26 (24.8) | 24 (38.7) | ||
B3 (penetrating) | 22 (52.4) | 41 (39.0) | 34 (54.8) | ||
Location | |||||
L1 (ileal) | 28 (66.7) | 25 (24.5) | 0.0001 | 17 (26.3) | 0.0001 |
Perianal disease | 0 | 6 (5.2) | 3 (4.8) | ||
L3 (ileocolonic) | |||||
Perianal disease | 14 (33.3) | 74 (69.4) | 45 (70.2) | ||
5 (11.9) | 40 (34.8) | 16 (25.8) |
Patients in the DS group are a subset of IMT patients. IMT: Initial medical therapy; DS: Deferred surgery; IQR: Interquartile range; M: Male; F: Female.