Table 1. Kinetic parameters for fTHP-9 hydrolysis by MT1-MMP.

MT1-MMP	Lipid	KM(μM)	kcat/KM (sec−1M−1)	kcat(s−1)
sMT1-MMP	None	4.23 ± 0.52	69,720 ± 3,317	0.30 ± 0.05
“	1% Bicelle	7.08 ± 0.41	106,700 ± 2,504	0.75 ± 0.05
“	5% Bicelle	8.85 ± 0.96	76,250 ± 2,716	0.67 ± 0.05
“	20% Bicelle	11.05 ± 1.02	60,710 ± 5,838	0.80 ± 0.26
“	1% Liposomes	8.2 ± 0.3	92,910 ± 6,768	0.76 ± 0.07
“	5% Liposomes	15.6 ± 1.52	67,300 ± 4,771	1.05 ± 0.18
“	20% Liposomes	11.2 ± 0.3	57,580 ± 3,770	0.80 ± 0.20
sMT1-MMP S466P	None	4.27 ± 0.76	79,750 ± 6,118	0.33 ± 0.037
“	1% Bicelle	4.98 ± 0.97	95,150 ± 2,328	0.47 ± 0.081
“	5% Bicelle	7.3 ± 0.45	62,570 ± 1,580	0.45 ± 0.017
“	20% Bicelle	11.18 ± 2.24	52,260 ± 13,900	0.63 ± 0.03
“	1% Liposomes	3.43 ± 0.12	104,200 ± 1,337	0.35 ± 0.009
“	5% Liposomes	7.15 ± 0.48	80,900 ± 9,324	0.58 ± 0.09
“	20% Liposomes	6.18 ± 0.23	77,920 ± 2,551	0.48 ± 0.03