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. Author manuscript; available in PMC: 2016 Jul 13.
Published in final edited form as: JAMA. 2015 Apr 21;313(15):1550–1563. doi: 10.1001/jama.2015.3253

Figure 1. Longitudinal evaluation of gene marking in blood cells after gene therapy.

Figure 1

(A). Gene marking in peripheral blood cells over time after gene therapy in patients P1 to P7, as expressed by vector copy numbers per cell (VCN) in PBMC and measured by q-PCR. (B). Gene marking in various blood cell subsets in each patient, expressed as VCN in: CD3+ T cells (filled squares); CD56+ NK cells (filled diamonds); CD19+ B cells (filled triangles); CD15+ neutrophils (open squares) and CD14+ monocytes (open circles).