Table 1.
Relationship of CDK5 expression with other clinicopathological variables
| Characteristic | Total number | No. patients, stratified by CDK5 | Z | P value | |
|---|---|---|---|---|---|
| Negative (228) | Positive (266) | ||||
| Age | −1.557 | 0.120a | |||
| ≤44 | 263 | 130 (49.4 %) | 133 (50.6 %) | ||
| >44 | 231 | 98 (42.4 %) | 133 (57.6 %) | ||
| Lymph node metastasis | −5.998 | <0.001a | |||
| Negative | 264 | 128 (48.5 %) | 136 (51.5 %) | ||
| Positive | 96 | 13 (13.5 %) | 83 (86.5 %) | ||
| Histological type | 32.490 | <0.001b | |||
| Chronic cervicitis | 54 | 39 (72.2 %) | 15 (27.8 %) | ||
| CA | 42 | 29 (69.0 %) | 13 (31.0 %) | ||
| Carcinoma in situ | 38 | 19 (50.0 %) | 19 (50.0 %) | ||
| Adenocarcinoma | 63 | 29 (46.0 %) | 34 (54.0 %) | ||
| SCC | 263 | 98 (37.3 %) | 165 (62.7 %) | ||
| Adenosquamous carcinoma | 34 | 14 (41.2 %) | 20 (58.8 %) | ||
| FIGO stage | −5.998 | <0.001a | |||
| I–II | 264 | 128 (48.5 %) | 136 (51.5 %) | ||
| III–IV | 96 | 13 (13.5 %) | 83 (86.5 %) | ||
| TNM stage | 52.911 | <0.001b | |||
| 0 | 38 | 19 (50.0 %) | 19 (50.0 %) | ||
| I | 248 | 128 (51.6 %) | 120 (48.4 %) | ||
| II–IV | 112 | 13 (11.6 %) | 99 (88.4 %) | ||
| Pathological grade | 23.604 | <0.001b | |||
| I | 28 | 16 (57.1 %) | 12 (42.9 %) | ||
| II | 157 | 77 (49.0 %) | 80 (51.0 %) | ||
| III | 141 | 34 (24.1 %) | 107 (75.9 %) | ||
CA condyloma acuminates, SCC squamous cell carcinoma, FIGO International Federation of Gynecology and Obstetrics, TNM tumor node metastasis
aTwo independent-samples Chi-square test was performed
bKruskal–Wallis H test was performed