Table 2.
Prostate cancer risk increase and ERF calculation (data from Multigner, 2010 [11])
| Exposure groups in the study (μg/Lblood) | ORmultivar (IC95 %) (−) | Delta OR (−) | Averaged exposure (μg/Lblood) | Delta Expo (μg/Lblood) | ERF (μg/Lblood)−1 |
|---|---|---|---|---|---|
| <0.25 (LD) | 1 | Ref. | 0.125a | Ref. | Ref. |
| >0.25 to 0.47 | 1.11 (0.75-1.65) | 0.11 | 0.360b | 0.235 | 0.468 |
| >0.47 to 0.96 | 1.22 (0.82-1.83) | 0.22 | 0.716b | 0.591 | 0.373 |
| >0.96* | 1.77 (1.21-2.58) | 0.77 | 6.866 c | 6.741 | 0.114 |
ERF are calculated with Eq. 1
Results in bold face are used to derive the ERF
LD = limit of detection. Ref. = reference group
Delta OR = OR - 1; delta expo = average exposure value – 0.125; ERF = delta OR/delta expo
* The maximal value in the study is 49.1 μg/L (cf. Guldner 2011 [127])
a = Value stated by Multignier et al. to compute the test for trend
b = arithmetic mean of the minimum and maximum values of this exposure group
c = geometric mean of the minimum and maximum values of this exposure group, respectively: 0.96 μg/L and 49.1 μg/L