Figure 2b:
Images in healthy 21-year-old female volunteer (body mass index: 19 kg/m2) show BAT activated by means of a cooling vest protocol (subject wore a cooling vest 1 hour before and 1 hour after FDG administration). (a) Axial CT scan at level of T1 vertebral body for anatomic reference shows supraclavicular fat (arrow). (b) Superimposed 18F-FDG PET scan shows FDG uptake in fat-attenuation regions, including supraclavicular (white arrow), paravertebral (black arrow), and intermuscular (arrowheads) regions. (c) Axial CT image at level of humeral heads for anatomic reference. (d) Fused 18F-FDG PET/CT scan shows FDG-avid adipose tissue in axillary (white arrow), paravertebral (black arrow), and upper mediastinal (arrowhead) regions. (e) Coronal reformatted CT scan for anatomic reference shows supraclavicular and axillary fat. (f) Fused 18F-FDG PET/CT scan shows FDG uptake in fat-attenuation areas, including supraclavicular (white arrow) and paravertebral (black arrow) regions. (g) Coronal multiple intensity projection image shows extensive uptake consistent with BAT throughout cervical, supraclavicular (white arrow), axillary, and paravertebral (black arrow) regions.