Table 1.
Data characteristics. ASSET: array spatial sensitivity encoding technique, FSPGR: fast spoiled gradient-recalled echo, IR: inversion recovery, MPRAGE: magnetization prepared rapid acquisition gradient echo, TE: echo time, TI: inversion time, TR: repetition time
| VUMC | EMC | UP | |
|---|---|---|---|
| Scanner | 3T, GE Healthcare | ||
| 3T, GE Healthcare | Protocol 1: Discovery MR750 | 3T, Siemens | |
| Signa HDxt | Protocol 2: Discovery MR750 | Trio A Tim | |
| Protocol 3: HD platform | |||
|
| |||
| Sequence | 3D IR FSPGR | 3D IR FSPGR | 3D MPRAGE |
|
| |||
| Scan parameters (TI/TR/TE) | 450ms / 7.8ms / 3.0ms | Protocol 1: 450ms / 7.9ms / 3.1ms | 900ms / 2300ms / 3.0ms |
| Protocol 2: 450ms / 6.1ms / 2.1ms | |||
| Protocol 3: 300ms / 10.4ms / 2.1ms | |||
|
| |||
| Parallel imaging | Yes (ASSET factor=2) | Protocol 1: Yes (ASSET factor=2) | No |
| Protocol 2: Parallel imaging: No | |||
| Protocol 3: Parallel imaging: No | |||
|
| |||
| Resolution | 0.9x0.9x1 mm (sagittal) | Protocol 1: 0.9x0.9x1.0 mm (sagittal) | 1x1x1.2 mm (sagittal) |
| Protocol 2: 0.9x0.9x0.8 mm (axial) | |||
| Protocol 3: 0.5x0.5x0.8 mm (axial) | |||
|
| |||
| Number of scans | 180 | 174 | 30 |
|
| |||
| Age Mean (Std) | |||
| Overall | 62.2 (5.9) years | 68.6 (7.8) years | 67.8 (9.1) years |
| CN | 62.1 (6.0) years | 65.5 (7.3) years | 64.1 (8.8) years |
| MCI | 62.5 (5.5) years | 73.1 (5.5) years | 70.0 (8.5) years |
| AD | 62.0 (6.0) years | 67.2 (8.4) years | 64.6 (7.8) years |
|
| |||
| Percentage of males | |||
| Overall | 59 % | 63 % | 50 % |
| CN | 62 % | 61 % | 40 % |
| MCI | 68 % | 69 % | 60 % |
| AD | 47 % | 57 % | 50 % |