Table 2.
Data regarding the second transplantation and outcome divided in BOS and rCLAD. Data are displayed as total number (%) or median (IQR). CLAD data is only presented for patients who survived at least 90 days post transplant. Other causes of death include cancer and heart failure.
| BOS | rCLAD | ||
|---|---|---|---|
| N | 94 (66%) | 49 (34%) | |
| Patients home prior to re-LTx | 36 (39%) of 92 | 26 (53%) | 0.091 |
| ECMO as bridge to transplant, n(%) | 7(8%) of 90 | 11 (23%) of 47 | 0.011 |
| Clamshell incision, n (%) | 51 (54%) | 28 (57%) | 0.74 |
| BMI at re-LTx | 19.1(17.1–21.9) | 19.4(16.7–23.9) | 0.42 |
| Age at re-LTx (y) | 35 (27–48) | 37 (30–50) | 0.49 |
| Operation time (min) | 410(308–500) | 445(382–575) | 0.050 |
| PGD score at 48 hours | 1.0 (0.0–2.0) of 79 | 2.0 (1.0–2.0) of 43 | 0.048 |
| Baseline FEV1 after re-LTx, L | 2.34 (1.95–2.88) | 2.10 (1.73–2.66) | 0.17 |
| CLAD after re-LTx, n(%)* | 26/87 (30%) | 14/34 (41%) | 0.43 |
| Patients died, n (%) | 37 (39%) | 31 (63%) | 0.0066 |
| Cause of death, n(%) | 0.064 | ||
| Postoperative (<90 days) | 6 (16%) | 12 (39%) | |
| CLAD/Graft failure | 12 (32%) | 13 (42%) | |
| Infection/sepsis | 13 (35%) | 4 (13%) | |
| Other | 4 (11%) | 2 (4%) | |
| Unknown | 2 | 0 |
Abbreviations: LTx: lung transplantation; BMI: Body mass index; PGD: primary graft dysfunction; FEV1: forced expiratory volume in 1 second; CLAD: chronic lung allograft dysfunction.
*
Data of CLAD was conditional on 90 days survival.