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. Author manuscript; available in PMC: 2016 Jul 13.
Published in final edited form as: N Engl J Med. 2011 Nov 1;365(20):1896–1904. doi: 10.1056/NEJMoa1110212

Table A.11.4.

Adjusted Hazard Ratio for Serious Cardiovascular Events, According to Use of ADHD Medications, Excluding Children with Serious Psychiatric Illness.

ADHD medication use Person-
years		 Events Rate/100,000 Hazard
Ratio† 		95%
confidence
interval
low		 95%
confidence
interval
high
Non-user 1,534,206 43 2.80 1.00 Ref Ref
Former user 457,171 10 2.19 0.82 0.36 1.86
Current user 280,306 3 1.07 0.66 0.20 2.16
†

Hazard ratios estimated with Cox regression models which included site-specific propensity score decile, site, medical conditions (serious cardiovascular disease, serious chronic illness), utilization variables (medical hospitalization and general medical care access), and calendar year.