Table 2.
Fistula Thrombosis
| No. (%) of Patients | Relative Risk (95% Confidence Interval)b |
||
|---|---|---|---|
| Clopidogrel (n = 435)a |
Placebo (n = 431)a |
||
| Thrombosis at 6 wk (all patients) | 53 (12.2) | 84 (19.5) | 0.63 (0.46–0.97)c |
| By location | |||
| Forearm fistula | 31 (12.9) | 60 (24.7) | 0.53 (0.36–0.77) |
| Upper arm fistula | 22 (11.3) | 24 (12.8) | 0.89 (0.52–1.53) |
a
Six of the 441 patients randomized to clopidogrel and 5 of the 436 patients randomized to placebo were not included because patency was not evaluated.
b
Relative risks were stratified for fistula location and center.
c
The 95% confidence interval reported is the repeated confidence interval adjusted for interim monitoring. The repeated P value adjusted for interim monitoring is .018.