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. Author manuscript; available in PMC: 2016 Jul 13.
Published in final edited form as: Neuroscience. 2013 Aug 29;253:132–141. doi: 10.1016/j.neuroscience.2013.08.035

Figure 3. Incision-induced cold hyperalgesia in WT, PRL KO and PRL-R KO female and male mice.

Figure 3

(A) Incision-induced cold hyperalgesia in WT and PRL KO female mice. Cold hyperalgesia is measured as changes ( ) from baseline measured before surgery in threshold temperature producing animal responses (Temperature °C; ***p<0.001; 2-way ANOVA; n=9). (B) Incision-induced cold hyperalgesia in WT and PRL KO male mice (Temperature °C; NS; 2-way ANOVA; n=9). (C) Incision-induced cold hyperalgesia in WT and PRL-R KO female mice (Temperature °C; **p<0.01; ***p<0.001; 2-way ANOVA; n=8). (D) Incision-induced cold hyperalgesia in WT and PRL-R KO male mice (Temperature °C; NS; 2-way ANOVA; n=8). Post-incision time points are indicated below X-axis. Mouse lines and sex (i.e F and M) are noted. WT, PRL KO and PRL-R KO shams are for n=5 (each).