Table 3.

Relative Risk for Mortality During the 4‐Year Follow‐Up, Stratified by the Severity of On‐Admission Hyponatremia

On‐Admission Sodium Levels	Cases/Deaths	Model 1	Model 2	Model 3	Model 4
		HR (95% CI)	HR (95% CI)	HR (95% CI)	HR (95% CI)
≥135 mEq/L	2196/859	1	1	1	1
125 to 134 mEq/L	329/162	1.58 (1.33–1.87)	1.52 (1.28–1.80)	1.28 (0.98–1.67)	2.64 (1.33–5.27)
<125 mEq/L	31/21	2.48 (1.61–3.82)	2.11 (1.37–3.27)	3.68 (2.04–6.64)	5.13 (1.15–22.83)

Model 1: crude ratio; Model 2: adjust for age and sex; Model 3: adjust for age, sex, hematocrit, estimated glomerular filtration rate, left ventricle ejection fraction, use of beta‐blocker, renin angiotensin system blockade, and spironolactone; model 4: model 3+NT‐proBNP (n=947).