Table 8.
VIP Scores in Analyses Contrasting Normal With Diastolic LV Dysfunction
| Metabolomic Biomarker | VIP Score |
|---|---|
| Lactate | 1.433 |
| 4‐Aminobutyrate | 1.411 |
| Glycoprotein | 1.403 |
| Valerate | 1.398 |
| Creatinine | 1.271 |
| 4‐Hydroxybutyrate | 1.269 |
| Alanine | 1.267 |
| Valine | 1.247 |
| Glucose+glutamine | 1.201 |
| Glucose | 1.187 |
| Glucose+2‐aminobutyrate | 1.185 |
| Glucose+2‐phosphoglycerate | 1.172 |
| Acetate | 1.143 |
| Phosphocholine | 1.142 |
| Threonine | 1.126 |
| 2‐Aminobutyrate | 1.112 |
| Leucine | 1.112 |
| Fatty acid with –CH=CH | 1.106 |
| 2‐Oxobutyrate | 1.027 |
| Fatty acid with α–CH2 | 1.024 |
| Creatine+creatine‐phosphate | 1.024 |
| α‐Glucose | 1.007 |
Variable Importance in Projection (VIP) scores estimate the importance of each variable in the projection used in a partial least square (PLS) model and is often used for variable selection. A variable with a VIP score greater than 1 can be considered important in a given model. LV indicates left ventricular.