Table 7.
Association Between a DII Calculated on the Basis of Energy‐Adjusted Nutritional Parameters (DII 2) and Incidence of Myocardial Infarction, SU.VI.MAX Study, France (N=7743)
Q1DII | Q2DII | Q3DII | Q4DII | P trend a | Continuous DII | P continuous | |
---|---|---|---|---|---|---|---|
DII, mean (IQR) | −1.86 (1.20) | −0.19 (0.92) | 0.91 (0.78) | 2.41 (1.00) | |||
N | 1935 | 1936 | 1937 | 1935 | |||
Number of cases | 19 | 19 | 29 | 26 | |||
Person‐time, y | 22 050 | 22 064 | 21 905 | 21 913 | |||
Model 0 | 1 (ref) | 1.05 [0.56–1.99] | 1.77 [0.99–3.16] | 1.71 [0.95–3.10] | 0.02b | 1.23 [1.09–1.39] | 0.001b |
Model 1 | 1 (ref) | 1.11 [0.59–2.10] | 1.96 [1.09–3.52] | 1.83 [1.00–3.33] | 0.01b | 1.15 [1.01–1.31] | 0.04b |
Model 2 | 1 (ref) | 1.08 [0.57–2.05] | 1.87 [1.03–3.37] | 1.59 [0.86–2.92] | 0.05 | 1.11 [0.98–1.27] | 0.11 |
Model 3a | 1 (ref) | 1.09 [0.57–2.06] | 1.88 [1.04–3.39] | 1.62 [0.88–2.97] | 0.04b | 1.12 [0.98–1.27] | 0.10 |
Model 3b | 1 (ref) | 1.07 [0.56–2.03] | 1.84 [1.01–3.33] | 1.56 [0.85–2.89] | 0.06 | 1.11 [0.97–1.26] | 0.13 |
Values are hazard ratio (95% CIs), estimated through Cox proportional hazard models, corresponding to sex‐specific quartiles of the DII. Model 0 is crude. Model 1 is adjusted for sex and energy intake without alcohol. Model 2: Model 1+supplementation group, number of 24‐h records, education level, marital status, smoking status, and physical activity. Model 3a: Model 2+body mass index. Model 3b: Model 2+alcohol consumption. DII indicates dietary inflammatory index; IQR, interquartile range; Q, sex‐specific quartile; SU.VI.MAX, Supplémentation en Vitamines et Minéraux AntioXydants.
P for trend (obtained by modeling DII quartiles as an ordinal variable).
P<0.05.