Table 1.

Participants Characteristics at Baseline, EDIC Study Year 1

	All Participants	Major Abnormality			Any Abnormality
		Yes (N=26)	No (N=1288)	P Valuea	Yes (N=356)	No (N=958)	P Valuea
Age, yr	35.1±7.0	36.1±7.8	35.1±7.0	0.46	34.7±7.1	35.2±6.9	0.30
Female (%)	47.5	53.9	47.4	0.51	41.6	49.7	0.009
Race (% white)	96.3	92.3	96.4	0.66	94.7	96.9	0.13
Intensive treatment group (%)	49.9	42.3	50.1	0.43	50.3	49.8	0.87
Primary cohort (%)	49.7	38.5	49.9	0.25	51.4	49.1	0.45
Duration of diabetes, yr	13.6±4.9	13.9±4.7	13.5±4.9	0.63	13.3±5.3	13.6±4.8	0.07
Current smoking (%)	19.2	23.1	19.1	0.61	16.6	20.2	0.14
Body mass index, kg/m2	26.1±4.0	26.4±4.5	26.1±4.0	0.91	25.7±3.7	26.3±4.1	0.030
Body mass index ≥30 kg/m2 (%)	13.7	15.4	13.7	0.80	11.5	14.5	0.16
Systolic blood pressure, mm Hg	117±12	123±17	117±12	0.11	118±13	117±12	0.97
Diastolic blood pressure, mm Hg	75±9	74±8	75±9	0.51	75±9	75±9	0.18
HbA1c (%)	8.1±1.4	8.2±1.4	8.1±1.4	0.90	8.1±1.4	8.1±1.3	0.20
Weighted mean HbA1c (%)	8.1±1.3	8.4±1.5	8.1±1.3	0.41	8.1±1.4	8.2±1.3	0.29
HDL cholesterol, mg/dL	54±14	58±16	54±14	0.18	54±14	54±14	0.63
Non‐HDL cholesterol, mg/dL	133±37	131±27	133±37	0.89	130±37	134±37	0.010
LDL cholesterol, mg/dL	115±31	113±22	115±31	0.91	113±32	116±31	0.021
Total cholesterol, mg/dL	187±36	190±25	187±36	0.43	183±36	188±36	0.008
Triglyceride, mg/dL	91±75	103±86	90±75	0.86	87±75	92±75	0.07
Microalbuminuria (%)	16.0	19.2	15.9	0.65	15.2	16.3	0.62

EDIC indicates Epidemiology of Diabetes Interventions and Complications (EDIC) Study; HbA1c, glycosylated hemoglobin; HDL, high‐density lipoprotein; LDL, low‐density lipoprotein.

^a P value is based on chi‐square test for categorical variables and Wilcoxon rank sum test for continuous variables.