Table 2.
Serum Values Measured at Baseline and Follow‐up According to the Study Groups
| Placebo Groupa (n=149) | Vitamin E Groupa (n=149) | P Value | |
|---|---|---|---|
| Serum creatinine, mg/dL | |||
| Baseline | 1.3 (1.2–1.5) | 1.3 (1.2–1.5) | 0.2 |
| Within 72 hours | 1.3 (1.1–1.5) | 1.3 (1.1–1.4) | 0.082 |
| Serum urea, mg/dL | |||
| Baseline | 52 (40–69) | 48 (38–65) | 0.2 |
| Within 72 hours | 45 (35–60) | 41 (33–53) | 0.073 |
| eGFR, mL/min per 1.73 m2 | |||
| Baseline | 44 (37–51) | 45 (39–53) | 0.3 |
| Within 72 hours | 49 (39–55) | 49 (41–59) | 0.1 |
| Serum Na+, mEq/L | |||
| Baseline | 141 (139–143) | 141 (140–144) | 0.057 |
| Within 72 hours | 141 (139–143) | 141 (139–142) | 0.5 |
| Serum K+, mEq/L | |||
| Baseline | 4.3 (3.9–4.6) | 4.3 (4–4.6) | 0.6 |
| Within 72 hours | 4.2 (4–4.4) | 4.2 (4–4.6) | 0.2 |
| WBC, ×103/mL | |||
| Baseline | 7.9 (6.26–9.7) | 7.8 (6.5–9) | 0.5 |
| Within 72 hours | 7.5 (6.3–8.9) | 7 (6–8.4) | 0.1 |
| Platelet count, ×103/L | |||
| Baseline | 215 (180–261) | 205 (168–245) | 0.077 |
| Within 72 hours | 189 (157–238) | 186 (156–222) | 0.3 |
| Hematocrit, % | |||
| Baseline | 39.3 (36.3–43.4) | 39.1 (36–41.6) | 0.4 |
| Within 72 hours | 38.3 (34–41.5) | 37.1 (34.3–41.1) | 0.5 |
| Hemoglobin, mg/dL | |||
| Baseline | 12.8 (11.3–13.5) | 12.3 (11.2–13.6) | 0.3 |
| Within 72 hours | 12.2 (10.9–13.2) | 12 (10.8–13.2) | 0.5 |
Values are presented as median (interquartile range). eGFR indicates estimated glomerular filtration rate; WBC, white blood cell.
a
Values were not provided for 6 and 3 patients during 72 hours in the placebo and vitamin E groups, respectively.