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. 2016 Mar 25;5(3):e002956. doi: 10.1161/JAHA.115.002956

Table 3.

ECG Variables Related to All‐Cause Mortality

Variables Age‐, Sex‐ and Cohort‐ Adjusted Multivariable Adjusteda ECG×Cohort ECG×Sex
HR (95% CI) P Value HR (95% CI) P Value Interaction P Interaction P
PR interval 1.03 (0.97, 1.09) 0.35 1.07 (1.01, 1.13) 0.03 0.79 0.48
QRS duration 1.09 (1.04, 1.15) 0.001 1.09 (1.03, 1.15) 0.003 0.49 0.67
QT interval 1.04 (0.97, 1.10) 0.26 1.25 (1.15, 1.36) <0.0001 0.53 0.44
QTcFram 1.15 (1.09, 1.22) <0.0001 1.15 (1.08, 1.22) <0.0001 0.98 0.01
QTcBaz 1.20 (1.13, 1.27) <0.0001 1.18 (1.11, 1.25) <0.0001 0.56 0.004
QRS voltage 1.15 (1.08, 1.23) <0.0001 1.12 (1.05, 1.20) 0.0009 0.045 0.28
LVH 1.93 (1.49, 2.50) <0.0001 1.73 (1.33, 2.24) <0.0001 0.02 0.14
Left atrial enlargement 1.58 (1.26, 1.99) <0.0001 1.41 (1.12, 1.77) 0.004 0.06 0.91
LBBB 1.41 (0.87, 2.28) 0.16 1.35 (0.83, 2.18) 0.2 0.68 0.91
RBBB 1.29 (0.99, 1.68) 0.06 1.21 (0.93, 1.58) 0.2 0.64 0.90

Hazard ratio is per SD change in continuous variables, and from comparison of the presence of dichotomous variables to their absence. CI indicates confidence interval; ECG, electrocardiogram; HR, hazard ratio; LBBB, left bundle branch block; LVH, left ventricular hypertrophy; RBBB, right bundle branch block.

a

Adjusted for body mass index, heart rate (except QTc), systolic blood pressure, antihypertensive therapy, diabetes, and smoking.