Table 1.
Baseline Characteristics of Patients Treated With Clopidogrel–Aspirin or Aspirin Alone Within 12 Hours
| Time to Randomization Within 12 Hours (N=2573) | |||
|---|---|---|---|
| Aspirin (n=1280) | Clopidogrel–Aspirin (n=1293) | P Value | |
| Age, y | |||
| Median | 62 | 63 | 0.05 |
| Interquartile range | 54 to 71 | 55 to 72 | |
| Female sex, n (%) | 441 (34.5) | 439 (34.0) | 0.79 |
| Systolic pressure, mm Hg | 0.54 | ||
| Median | 150 | 150 | |
| Interquartile range | 135 to 160 | 136 to 161 | |
| Diastolic pressure, mm Hg | 0.58 | ||
| Median | 90 | 90 | |
| Interquartile range | 80 to 100 | 80 to 98 | |
| Body‐mass indexa | 0.57 | ||
| Median | 24.5 | 24.5 | |
| IQR | 22.9–26.6 | 22.7–26.5 | |
| Medical history, n (%) | |||
| Ischemic stroke | 273 (21.3) | 295 (22.8) | 0.36 |
| TIA | 47 (3.7) | 45 (3.5) | 0.79 |
| Myocardial infarction | 31 (2.4) | 27 (2.1) | 0.57 |
| Angina | 48 (3.8) | 44 (3.4) | 0.64 |
| Congestive heart failure | 18 (1.4) | 20 (1.6) | 0.77 |
| Known atrial fibrillation or flutter | 29 (2.3) | 24 (1.9) | 0.46 |
| Valvular heart disease | 3 (0.2) | 1 (0.1) | 0.61 |
| Hypertension | 831 (64.9) | 867 (67.1) | 0.25 |
| Diabetes mellitus | 256 (20.0) | 299 (23.1) | 0.05 |
| Hypercholesterolemia | 139 (10.9) | 140 (10.8) | 0.98 |
| Pulmonary embolism | 1 (0.1) | 0 (0.0) | 0.50 |
| Current or previous smoking, n (%) | 536 (41.9) | 524 (40.5) | 0.49 |
| ABCD2 scoreb | 0.57 | ||
| Median | 4 | 4 | |
| IQR | 4 to 5 | 4 to 5 | |
TIA indicates transient ischemic attack.
a
The bodyvmass index is the weight in kilograms divided by the square of the height in meters.
b
Data are only for patients who had a TIA. The ABCD2 score assesses the risk of stroke on the basis of age, blood pressure, clinical features, duration of TIA, and presence or absence of diabetes, with scores ranging from 0 to 7 and higher scores indicating greater short‐term risk.