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. 2016 Mar 15;5(3):e003126. doi: 10.1161/JAHA.115.003126

Figure 7.

Figure 7

Improved cardiac function in response to TAC‐induced heart failure in ICAM1−/− mice. A through C, Invasive hemodynamic measurements in WT and ICAM1−/− mice measured at 4 weeks after TAC and sham surgery (n=3 WT, n=6–12 ICAM1−/−), (A) end‐diastolic pressure, (B) maximum pressure (C) contractile function (dP/dtmax), and (D) relaxation function (dP/dtmin). E, Fractional shortening at 4 weeks after sham or TAC surgery in WT and ICAM1−/− mice (n=3–6 sham, n=5–10 TAC). Statistical analysis used the unpaired t test. *P<0.05, **P<0.01, ***P<0.005. FS indicates fractional shortening; ICAM1 indicates intercellular cell adhesion molecule 1; TAC, transverse aortic constriction; WT, wild type.