Skip to main content
. Author manuscript; available in PMC: 2016 Jul 13.
Published in final edited form as: Alkaloids Chem Biol. 2005;61:59–262. doi: 10.1016/s1099-4831(05)61002-4

TABLE XI.

Antiviral Activity of Bromotyrosine Derivatives

Alkaloids Antiviral activity Ref.
Moloka'iamine (52) Mv 1 Lu/HSV II: 10 μg/mL 92% reduced; CV-1/HSV-1 and BHK/VSV not active 42
Mololipids (53) HIV-1 ED50 52.2 μM 43
Fistularin-3 (79) Feline leukemia [ED50:22 μM (4.8 μg/200 μl)]. ED50: AZT 0.10 μM, ED50: ddCyd 15 μM. Not active against FeLV at 100 μg/200 μl 71
11-Ketofistularin-3 (82) Feline leukemia [ED50:42 μM (9.3 μg/200 μl)]. ED50: AZT 0.10 μM, ED50: ddCyd 15 μM. Not active against FeLV at 100 μg/200 μl 71
Psammaplysin D (132) 51% inhibition at 0.1 μg/mL against Haitian RF stran of HIV-1 96