Table 6.
Selection of variables significantly associated with hospital mortality using multivariate logistic regression, within each of the four components of PIRO
| Variables | Odds ratio | 95% confidence interval | P value |
|---|---|---|---|
| Predisposition (P) | |||
| Age >70 years | 4.97 | 1.19-20.82 | 0.028 |
| COPD* | 10.34 | 1.90-56.10 | 0.007 |
| CLD† | 5.75 | 1.69-19.59 | 0.005 |
| Cancer | 20.94 | 2.36-186.12 | 0.006 |
| Presence of foley’s catheter | 6.11 | 2.77-13.50 | <0.001 |
| Infection (I) | |||
| Pneumonia | 2.45 | 1.17-5.11 | 0.017 |
| Meningitis/encephalitis | 8.07 | 1.68-38.73 | 0.009 |
| UTI‡ | 4.81 | 1.64-14.14 | 0.004 |
| Response (R) | |||
| Band (>5%) | 2.49 | 1.35-4.61 | 0.004 |
| Respiratory rate (>20/min) | 3.72 | 1.34-10.38 | 0.012 |
| Organ dysfunction(O) | |||
| SBP§ <90 mmHg | 2.13 | 1.08-4.22 | 0.028 |
| PaO2/FiO2 ||<300 | 2.52 | 1.26-5.00 | 0.008 |
| Urine output in first 2 hours <30 ml | 2.93 | 1.34-5.93 | 0.006 |
| APTT¶ >35 seconds | 2.04 | 1.06-4.53 | 0.034 |
| Creatinine >1.8 mg/dL | 2.12 | 1.06-4.63 | 0.033 |
| GCS** ≤9 | 6.02 | 2.24-16.19 | 0.001 |
*COPD= Chronic obstructive pulmonary disease; †CLD= Chronic liver disease; ‡UTI = Urinary tract infection; §SBP= Systolic blood pressure; ||PaO2/FiO2 = Partial pressure of oxygen in arterial blood/Fraction of inspired oxygen; APTT = Activated partial thromboplastin time; **GCS = Glasgow coma scale