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. 2015 Oct-Dec;61(4):235–242. doi: 10.4103/0022-3859.166511

Table 6.

Selection of variables significantly associated with hospital mortality using multivariate logistic regression, within each of the four components of PIRO

Variables Odds ratio 95% confidence interval P value
Predisposition (P)
 Age >70 years 4.97 1.19-20.82 0.028
 COPD* 10.34 1.90-56.10 0.007
 CLD 5.75 1.69-19.59 0.005
 Cancer 20.94 2.36-186.12 0.006
 Presence of foley’s catheter 6.11 2.77-13.50 <0.001
Infection (I)
 Pneumonia 2.45 1.17-5.11 0.017
 Meningitis/encephalitis 8.07 1.68-38.73 0.009
 UTI 4.81 1.64-14.14 0.004
Response (R)
 Band (>5%) 2.49 1.35-4.61 0.004
 Respiratory rate (>20/min) 3.72 1.34-10.38 0.012
Organ dysfunction(O)
 SBP§ <90 mmHg 2.13 1.08-4.22 0.028
 PaO2/FiO2 ||<300 2.52 1.26-5.00 0.008
 Urine output in first 2 hours <30 ml 2.93 1.34-5.93 0.006
 APTT >35 seconds 2.04 1.06-4.53 0.034
 Creatinine >1.8 mg/dL 2.12 1.06-4.63 0.033
 GCS** ≤9 6.02 2.24-16.19 0.001

*COPD= Chronic obstructive pulmonary disease; CLD= Chronic liver disease; UTI = Urinary tract infection; §SBP= Systolic blood pressure; ||PaO2/FiO2 = Partial pressure of oxygen in arterial blood/Fraction of inspired oxygen; APTT = Activated partial thromboplastin time; **GCS = Glasgow coma scale