Figure 3.

Relationship between cumulative VSLI exposure, the worst grade of related vincristine-induced peripheral neuropathy (VIPN) adverse events, and response [54]. Blue rectangles in the left-hand column above each grade of VIPN represent nonresponders; blue diamonds in the right-hand column represent patients who achieved a partial remission or bone marrow blast response; gold diamonds represent patients who achieved complete remission (CR) or CR with incomplete hematologic recovery (CRi). Responses, including CR or CRi, were achieved at each grade of related VIPN.

Abbreviation: VSLI, vincristine sulfate liposome injection.