Table 1. Experimental groups.
Animal model | Adult SD rat | Adult minipig | ||||
---|---|---|---|---|---|---|
Segmental level | Cervical | Thoracic | Lumbar | Cervical | Thoracic | Lumbar |
Intrathecal AAV9 | – | – | N = 5 (&) | – | – | – |
Subpial AAV9 | N = 4*; N = 4* (&) | – | N = 6 # | – | N = 4 & | N = 4 (#) |
–AAV9-UBI-GFP
–AAV9-UBI-RFP
–6 months survival
– 6–8 weeks months survival.