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. 2016 Jun 16;22(7):663–670. doi: 10.1089/ten.tec.2015.0562

FIG. 4.

FIG. 4.

Relative expression of markers related to EPCs and endothelialization. mRNA fold increases are presented over 14 days of culturing in either static or dynamic cultures. TEVGs generally demonstrated expression of endothelial markers consistent with mature ECs over time (increased CD31, NOS3, and vWF, decreased CD34); whereas dynamically cultured TEVGs showed increased expression of vWF and VEGF, indicative of endothelial maturation and function. *Represents statistical significance compared with initial (day 0), and #represents statistical significance compared with all other groups within the time point (p < 0.05). EC, endothelial cell; NOS3, nitric oxide synthase 3; VEGF, vascular endothelial growth factor; vWF, von Willebrand Factor.